Hidden Costs of Prescription Medications: What You’re Really Paying For

Hidden Costs of Prescription Medications: What You’re Really Paying For

Chethan Sarabu, MD

Nov 24, 2024

Imagine this: You head to the pharmacy to pick up a medication your doctor prescribed, expecting to pay the $20 copay listed on your insurance plan. Instead, the pharmacist tells you it’s $150—because your plan doesn’t cover the exact brand your doctor prescribed, even though there’s no cheaper alternative. Confused? You’re not alone. Prescription drug pricing is a tangled web of hidden costs and understanding how the system works can help you avoid paying more than you should.

The Invisible Players Behind Your Prescription Costs

You may think the price of your medication is set by the manufacturer—but there’s more to the story. Behind the scenes, several players influence the final cost you pay:

  1. Pharmacy Benefit Managers (PBMs):

    PBMs act as middlemen between drug manufacturers, insurers, and pharmacies. They negotiate rebates and discounts from drug companies but don’t always pass those savings on to you. Instead, PBMs often pocket a portion of the rebate, inflating the price you pay at the pharmacy counter.

    Anecdote:  In 2019, the diabetes medication insulin made headlines when patients reported paying hundreds of dollars per month out-of-pocket despite manufacturers offering significant rebates. Much of the markup stemmed from PBM-negotiated pricing structures. The Federal Trade Commission (FTC) has recently sued the PBMs because of this as covered in a recent New York Times article.

  2. Tiered Formularies:

    Insurance plans group medications into tiers, with each tier dictating how much you’ll pay. Generic drugs might be in the lowest (cheapest) tier, while brand-name or specialty drugs sit in higher, pricier tiers. What you pay depends on where your medication falls and switching to a lower-tier option isn’t always possible if your doctor prescribes a specific drug.

  3. Spread Pricing:

    Some PBMs charge insurers more for a drug than what they reimburse pharmacies, keeping the difference as profit. This practice, called spread pricing, can drive up costs for patients in the form of higher premiums or out-of-pocket expenses.

Why Are Prescription Drugs So Expensive?

The U.S. lacks consistent regulation around drug pricing, making it an outlier compared to many other countries. Here are some reasons for high costs:

  • Patent Protections: Drug manufacturers can hold exclusive rights to produce a medication for years, allowing them to set high prices without competition.

  • Generic Delays: Manufacturers sometimes use legal tactics to delay the release of cheaper generic versions of their drugs.

  • Marketing Costs: U.S. companies spend billions annually on direct-to-consumer advertising, a practice not allowed in most countries, and these costs are baked into drug prices.

Strategies to Save on Prescription Medications

The good news? You can take steps to reduce the financial burden of prescription drugs. Here’s how:

  1. Ask About Generics or Alternatives:

    Always ask your doctor or pharmacist if there’s a generic or lower-cost alternative to the prescribed medication. Generics can be up to 85% cheaper than brand-name drugs.

  2. Shop Around:

    Prices can vary significantly between pharmacies, even for the same medication. Use tools like GoodRx or SingleCare to compare prices and find discounts.

  3. Look Into Patient Assistance Programs:

    Many drug manufacturers offer assistance programs that provide free or discounted medications to eligible patients. Nonprofits like NeedyMeds can help you find these programs.

  4. Consider Mail-Order Pharmacies:

    Mail-order options through your insurance or independent services often offer lower prices for chronic medications.

  5. Advocate for Price Transparency:

    Some states require pharmacies to disclose cash prices, which can sometimes be cheaper than insurance copays. Always ask for the cash price as a comparison.

The Path Forward: How Policies and Innovations Can Help

Efforts to lower prescription drug costs are gaining traction. For example:

  • The Inflation Reduction Act of 2022 introduced caps on out-of-pocket insulin costs for Medicare beneficiaries and aims to allow Medicare to negotiate drug prices directly with manufacturers starting in 2026.

  • Some states, like California, are exploring ways to produce their own generic drugs to combat high prices.

  • Companies like Mark Cuban Cost Plus Drugs are also trying to change how drugs are priced, sold, and even manufactured to pass on more savings to patients. 

The hidden costs of prescription medications can feel overwhelming, but understanding the factors at play—and knowing your options—can help you take control. Whether it’s switching to a generic, using price comparison tools, or exploring assistance programs, small steps can lead to significant savings.